pc加拿大

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科研进展

2020年06月17日
中国科大阐明秀丽隐杆线虫产生稳健而灵活运动的神经环路机制和算法

近日,中国科学技术大学生命科学学院、合肥微尺度物质科学国家研究中心、中科院脑科学与智能技术卓越创新中心温泉教授研究组在eLife 期刊上在线发表题为Flexible motor sequence generation during stereotyped escape responses的长篇研究论文。该研究结合实验和理论分析,揭示出秀丽隐杆线虫(以下简称线虫)在逃逸行为中产生稳健而灵活运动的神经环路机制和算法。

pc加拿大shengwutideyundongxingweijijingranyouxuyoufengfuduoyang。yibanrenwei,zheishiyouyixiliebaoshoudejichuyundongmokuailinghuozuheercheng。weiletansuoheshiyinghuanjing,shenjingxitongshiruhechanshengfuzaduobiandeyundongxulierengranshiweijiezhimi。


pc加拿大youxuerduoyangdeyundongxulieshiyitu

wenquanjiaoshouyanjiuzuyixianchongweiyanjiuduixiang,tanjiushengwutichanshengwenjianerlinghuoyundongxuliedeshenjinghuanlujizhi。xianchongshiyizhonglixiangdeyanjiushenjingshengwuxuedemoshishengwu,qishenjingxitongxiangduijiandandangongnengqiquan,chengchongzhiyou302geshenjingyuan,yue6400gehuaxuetuchuyijiyue890gediantuchu(white et al., 1986)。zai20shiji80niandai,xianchongwanzhengdeshenjingwangluolianjietupujiubeiwhite jgdengrentongguodianjingzhonggoudaotuchufenbianlvjibie,weishenjinghuanludeyanjiudaxialejichu(white et al., 1986);xianchongtongtitouming,feichangshiheyiguangxuedefangshiduishenjingyuanhuodongjinxingcaokonghejiance;xianchongdeyundongmoshijianjiedanbujiandan,shijieheshiyanhelilunyanjiuyundongkongzhidelixiangmoxing。


xianchongtaoyixingweishiyitu

xianchongzaishoudaowaijieqianzaiweixianheweixieshi,lirujixiecijihuozhereciji,huiwenjiandichufataoyixingwei。zheizhongtaoyixingweijuyoubaoshoudezuchengmokuai(qianjinyundong,houtuiyundong,zhuanwanyundong),danshimeigeyundongmokuaidechuxianxulieheyanxushijianquedabuxiangtong。zongheguangyichuanjishu、gaichengxiangjishu、hejisuanjianmo,yanjiuzufaxian: mokuaizhijiandexingfenxingqiankuitonglukeyijieshiweihewaijiecijinengwenjiandichufamouzhongyundongxulie;erbutongyundongmokuaizhijianyoutongguoxianghuyizhishixingyingjiatongchi(winner-take-all),congershixianbutongyundongfangshizhijiandelinghuozhuanyi。duanshichengtuchukesuxingyijishenjingxitongdeneibingzaoshengyezaidiaokongyundongshixuguochengzhongbanyanzhongyaojiaose。jiezhuxianchongdeshenjingwangluolianjietupuhefenzishengwuxuejishu,yanjiuzujinyibujiandingchuqiankuideshenjingtongluyilaiyuzhongjianshenjingyuanheyundongshenjingyuanzhijiandediantuchu;mokuaizhijiandexianghuyizhizeyilaishangyoushenjingyuanshifangguansuannengshenjingdizhihexiayoushenjingyuanbiaodaxiangyingdelvlizitongdao。

xianchongtaoyixingweidexianxiangxuemoxing

pc加拿大benyanjiuzaixianchongzheiyijianjiejincoudeshenjingxitongzhong,jiandingchushixianlinghuoerwenjianyundongdeshenjinghuanlusuanfa;weilijiegenggaodengshengwuyundongkongzhidejibenyuanlitichuleyizhongkeneng;yeweixiayidaileinaojiqideshejitigonglelingganhesilu。

pc加拿大benlunwendegongtongdiyizuozheweiwenquanjiaoshouyanjiuzuyanjiushengwangyuan、zhangxiaoqianhekaneijimeilongdaxueyanjiushengxinqi(kedawulixibenke),tongxunzuozheweiwenquanjiaoshou,tongshigaigongzuohaiyouduolunduodaxuezhenmeijiaoshouyanjiuzu、masazhusaiyixueyuandemark j. alkemajiaoshouyanjiuzudecanyu。gaixiangmudedaoleguojiazirankexuejijin(wenquan),zhongguokexueyuanzhanlvexingxiandaokejizhuanxiang(wenquan),guangdongshengzhongdianlingyuyanfajihua(wenquan)hejianadajiankangyanjiusuojijin(zhenmei)dezhichi。

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(shengmingkexuexueyuan、hefeiweichiduwuzhikexueguojiayanjiuzhongxin、zhongkeyuannaokexueyuzhinengjishuzhuoyuechuangxinzhongxin、keyanbu)


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